歡迎光臨北京索萊寶科技有限公司網站!
          銷售咨詢熱線:
          18101056239
          產品目錄
          相關文章
          您的位置: 網站首頁 > 產品中心 > > > bs-1252R一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體
          • 一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體
          產品名稱:

          一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體

          產品品牌: SOLARBIO/索萊寶 價格:
          廠商性質: 生產廠家 產品時間: 2024-07-09
          一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體
          貨號:bs-1252R
          規格:0.1ml/0.2ml
          產品應用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 (石蠟切片需做抗原修復)
          not yet tested in other applications.

          產品概述

          品牌SOLARBIO/索萊寶

           一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體

          產品編號bs-1252R
          英文名稱API5
          中文名稱凋亡抑制因子5抗體
          別    名apoptosis inhibitor 5; apoptosis inhibitory protein 5; API5; AAC-11; AAC11; API5L1; AAC 11; Antiapoptosis clone 11 protein; API5 like 1; Cell migration inducing gene 8 protein; Fibroblast growth factor 2 interacting factor 2; FIF; Migration inducing protein MIG8; MIG 8; MIG8; Protein XAGL; API5_HUMAN.
          研究領域腫瘤  免疫學  細胞凋亡  
          抗體來源Rabbit
          克隆類型Polyclonal
          交叉反應Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, 
          產品應用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 (石蠟切片需做抗原修復) 
          not yet tested in other applications.
          optimal dilutions/concentrations should be determined by the end user.
          分 子 量57kDa
          細胞定位細胞核 細胞漿 
          性    狀Lyophilized or Liquid111
          濃    度1mg/1ml
          免 疫 原KLH conjugated synthetic peptide derived from human API5
          亞    型IgG
          純化方法affinity purified by Protein A
          儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
          保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
          生 產 商BIOSS
          PubMedPubMed
          產品介紹background:
          Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. API5 expression is often upregulated in tumor cells, particularly in metastatic cells. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Alternate Names: AAC 11; AAC11; Antiapoptosis clone 11 protein; API 5; API5; API5 like 1; API5L1; Cell migration inducing gene 8 protein; Fibroblast growth factor 2 interacting factor 2; FIF; MIG 8; MIG8; Migration inducing protein MIG8; Protein XAGL.

          Function:
          Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

          Subunit:
          Monomer. Interacts with FGF2 and ACIN1.

          Subcellular Location:
          Nucleus. Cytoplasm. Note=Mainly nuclear. Can also be cytoplasmic. 
          Isoform 3: Cytoplasm.

          Tissue Specificity:
          Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.

          Post-translational modifications:
          Acetylation at Lys-251 impairs antiapoptotic function.

          Similarity:
          Belongs to the API5 family.

          Gene ID:
          8539

          Database links:

          Entrez Gene: 8539 Human

          Entrez Gene: 11800 Mouse

          Omim: 609774 Human

          SwissProt: Q9BZZ5 Human

          SwissProt: O35841 Mouse

          Unigene: 435771 Human

          Unigene: 181824 Mouse

          Unigene: 402557 Mouse



          Important Note:
          This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

          IAP-5是細胞凋亡的一種抑制因子、參與細胞凋亡調控,可以用于各種惡性腫瘤的細胞凋亡的研究.
          產品圖片

          Antigen: bs-1252P, 0.2ug/100ul 
          Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; 
          Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; 
          TMB(C-0024) staining; 
          Read the data in MicroplateReader by 450nm. 

          Protein: mouse heart lysates(A); mouse pancreas lysates(B); 
          Primary: Anti-API5 (bs-1252R) at 1:300; 
          Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP) at 1: 5000; 
          ECL excitated the fluorescence; 
          Predicted band size : 57 kD
          Observed band size :57 kD

          每一種抗體可以分別標記20種不同的標記物:

          Alexa Fluor 350 APCCy7 HRP
          Alexa Fluor 488Biotin FITC PE 
          Alexa Fluor 555 Cy3 Gold RBITC
          Alexa Fluor 647 Cy5.5  PE-Cy3PE-CY7
          AP Cy5 PE-CY5PE-CY5.5 

          一抗-多抗 Rabbit Anti-API5 antibody凋亡抑制因子5抗體訂購說明:

          1、絕大部分產品備有現貨,一般情況下都能訂貨當日發貨。 
          2、部分非常用產品,需提前1-2日預訂,海外期貨則需要提前3-6周預訂。 
          3、部分產品價格會因貨期、批次等因素發生變化,若有變動以訂貨當日價格為準。 
          4、每日訂單截止時間為16點整,部分城市可到17點整,因超過截止時間造成當日不能發貨的將于次日安排發貨。
          5、請辦理完貨款后,將收據、底單等連同收貨人的地址、姓名、電話等以傳真、EMail、短信、電話等形式通知我們。


          運輸說明:

          1、極低溫產品:極低溫產品運輸過程中加裝干冰運輸。用干冰把產品包裹起來,再用泡沫盒密封,膠帶層層粘住泡沫盒,放入索萊寶的箱子,然后交付給合作快遞,安全快速高效放心的送客戶的手中,保證產品的性質穩定如一,為您的實驗保駕護航。
          2、低溫產品:低溫產品運輸過程中加裝索萊寶冰袋運輸。事先用冰袋把產品包裹起來,再使用泡沫盒密封,用膠帶嚴實密封泡沫盒,再放入索萊寶的箱子(保溫效果少可以持續一周),然后交付給合作快遞,安全快速高效放心的送客戶的手中,保證產品的性質穩定如一,為您的實驗保駕護航。
          3、常溫產品:常溫產品運輸過程中無需加冰或者特殊包裝。產品由公司庫房人員快速配貨,準確快速高效的快遞保證產品快速送達您的手中。 

          留言框

          • 產品:

          • 您的單位:

          • 您的姓名:

          • 聯系電話:

          • 常用郵箱:

          • 省份:

          • 詳細地址:

          • 補充說明:

          • 驗證碼:

            請輸入計算結果(填寫阿拉伯數字),如:三加四=7
          六月婷婷国产精品综合| 少妇人妻偷人精品无码视频| 日韩精品无码Av一区二区| 久久99这里只有精品国产| 久久亚洲私人国产精品| 极品精品国产超清自在线观看| 国产精品热久久毛片| 亚洲国产日韩女人aaaaaa毛片在线 | 精品一区二区三区视频在线观看| 国产乱码精品一区二区三区| 亚洲精品自拍视频| 国内大量偷窥精品视频| 精品91自产拍在线观看二区| 亚洲毛片基地日韩毛片基地| 成人久久伊人精品伊人| 国产四虎免费精品视频| 久久国产热精品波多野结衣AV| 久久er国产精品免费观看2| 国产精品1024视频| 中文字幕无码日韩欧毛| 国产精品久久久久久福利| 亚洲av永久无码精品网址| 亚洲精品中文字幕乱码影院| 久久久久女人精品毛片九一| 91精品视频网站| 久草这里只有精品| 日韩人妻无码一区二区三区久久99| 国产精品无码免费播放| 亚洲中文字幕久久精品无码A | 四虎国产精品永久在线看| 欧美交A欧美精品喷水| 91freevideos精品| 久久久999久久久精品| 国产精品偷伦视频免费观看了| 精品久久久无码人妻中文字幕| 国产一精品一AV一免费| 精品视频一区二区三区| 亚洲国产精品激情在线观看| 国产精品视频视频久久| 亚洲精品综合在线影院| 91精品国产91久久久久久青草|