產品型號:K106464P
更新時間:2022-08-15
廠商性質:生產廠家
訪 問 量 :906
010-50973130
產品分類
Anti-Smac Polyclonal Antibody
英文名稱 | Anti-Smac Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | DIABLO;DFNA64;Diablo homolog;mitochondrial;SMAC 3;DBOH |
應用 | WB |
稀釋比例 | WB 1:3000. |
交叉反應 | Human Mouse Rat |
蛋白分子量 | 27kDa |
Gene ID | 56616 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human Smac |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human Smac |
Subcellular Locations | Cytoplasm |
Swiss Prot | Q9NR28 |
克隆類型 | Polyclonal Antibody |
背景資料 | This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. |