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專注于生物學(xué)試劑及試劑盒領(lǐng)域
服務(wù)熱線：010-50973130
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產(chǎn)品中心抗體Polyclonal AntibodyK106415PAnti-FINC Polyclonal Antibody
產(chǎn)品型號(hào)：K106415P
更新時(shí)間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
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產(chǎn)品分類
Anti-FINC Polyclonal Antibody
| 英文名稱 | Anti-FINC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | Fn1;FN;Fibronectin;FNZ;GFND;GFND2 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Mouse Rat |
| 蛋白分子量 | 272kDa |
| Gene ID | 14286 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human FINC |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human FINC |
| Subcellular Locations | Extracellular matrix |
| Swiss Prot | P11276 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
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